PYRANTEL oral

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    Therapeutic action

    • Anthelminthic

    Indications

    • Ascariasis
    • Enterobiasis
    • Ancylostomiasis
    • Trichinellosis

    Forms and strengths

    • 250 mg pyrantel embonate chewable tablet
    • Oral suspension, 50 mg pyrantel embonate per ml

    Dosage and duration

    Ascariasis

    • Child and adult: 10 mg/kg single dose
       

    Enterobiasis

    • Child and adult: 10 mg/kg single dose followed by a second dose after 2 to 4 weeks

     

    Ancylostomiasis

    • Child and adult: 10 mg/kg single dose; in severe infection, 10 mg/kg once daily for 4 days

     

    Trichinellosis

    • Child and adult: 10 mg/kg once daily for 5 days

    Contra-indications, adverse effects, precautions

    • May cause: gastrointestinal disturbances, headache, dizziness, drowsiness, skin rash.
    • Reduce dosage in patients with hepatic impairment.
    • Pregnancy: avoid during the first trimester
    • Breast-feeding: no contra-indication

    Remarks

    • Preferably use albendazole or mebendazole for these indications. However, when these drugs are contra-indicated, e.g. in children under one year, pyrantel is an alternative.

    Storage

     
    –  Below 25 °C