SPECTINOMYCIN injectable

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    Prescription under medical supervision

     

     
    Cephalosporins are the first choice treatment of gonococcal infections. Spectinomycin may be used as an alternative, when cephalosporins are not available or are contra-indicated.

     

    Therapeutic action

    • Antibacterial (group of aminoglycosides)

    Indications

    • Second choice treatment of gonococcal infections

    Forms and strengths, route of administration

    • Powder for injection in 2 g vial, to be dissolved with the diluent supplied by the manufacturer (3.2 ml ampoule of water for injection with benzyl alcohol), for IM injection

    Dosage and duration

    Anogenital gonococcal infection and gonococcal conjunctivitis

    • Adult: 2 g single dose (a dose of 4 g may be required, i.e. 2 g in each buttock)

     

    Disseminated gonococcal infection

    • Adult: 2 g every 12 hours for 7 days

    Contra-indications, adverse effects, precautions

    • May cause: nausea, dizziness, fever and chills, urticaria; pain at injection site.
    • Pregnancy: CONTRA-INDICATED (safety is not established)
    • Breast-feeding: no contra-indication for a single dose treatment

    Remarks

    • Administer a concurrent anti-chlamydia treatment to patients with gonococcal infections (co-infections are frequent).
    • Spectinomycin is poorly effective against pharyngeal gonococcal infections.
    • For the treatment of neonatal gonococcal conjunctivitis, use cephalosporins.
    • Shake well prior to withdrawal medication and use a 19G needle.
    • Do not mix with other drugs in the same syringe.

    Storage

    Below 25 °C