MODIFIED FLUID GELATIN (Plasmion®...)

Prescription under medical supervision


Therapeutic action

– Colloidal plasma substitute

Indications

– Fluid replacement in hypovolaemic shock (haemorrhagic shock, septic shock)

Forms and strengths

– 500 ml plastic bottle or bag

Composition

– Varies according to the manufacturer.
Example:


Plasmion®

Haemaccel®

Modified fluid gelatin

30 g/litre

Polygeline

35 g/litre

Sodium (Na+)

150 mmol (150 mEq)

145 mmol (145 mEq)

Potassium (K+)

5 mmol (5 mEq)

5.10 mmol (5.10 mEq)

Calcium (Ca++)

6.25 mmol (12.50 mEq)

Chloride (Cl)

100 mmol (100 mEq)

145 mmol (145 mEq)

Magnesium (Mg++)

1.5 mmol (3 mEq)

Lactate

30 mmol (30 mEq)

Dosage

– Adjust dosage according to the patient’s haemodynamic status.
– In the event of haemorrhage, replace the lost volume by the same volume of plasma substitute.

Contra-indications, adverse effects, precautions

– May cause: allergic reactions, possibly severe (anaphylactic shock).
– PregnancyCONTRA-INDICATED: risk of maternal anaphylactic reaction with serious consequences for the foetus. Use Ringer lactate.

Remarks

– Do not add any drugs to the bottle.
– When plasma substitutes are not available, use Ringer lactate (giving 3 times the lost blood volume).
– Storage: below 25 °C