PYRANTEL oral


Therapeutic action

– Anthelminthic

Indications

– Ascariasis
– Enterobiasis
– Ancylostomiasis
– Trichinellosis

Forms and strengths

– 250 mg pyrantel embonate chewable tablet
– Oral suspension, 50 mg pyrantel embonate per ml

Dosage and duration

– Ascariasis
Child and adult: 10 mg/kg single dose

– Enterobiasis
Child and adult: 10 mg/kg single dose followed by a second dose after 2 to 4 weeks

– Ancylostomiasis
Child and adult: 10 mg/kg single dose; in severe infection, 10 mg/kg once daily for 4 days

– Trichinellosis
Child and adult: 10 mg/kg once daily for 5 days

Contra-indications, adverse effects, precautions

– May cause: gastrointestinal disturbances, headache, dizziness, drowsiness, skin rash.
– Reduce dosage in patients with hepatic impairment.
– Pregnancy: avoid during the first trimester
– Breast-feeding: no contra-indication

Remarks

– Preferably use albendazole or mebendazole for these indications. However, when these drugs are contra-indicated, e.g. in children under one year, pyrantel is an alternative.
 Storage: below 25 °C -