12.2 Prophylaxis against opportunistic infections

It is recommended that cotrimoxazole preventive therapy (CPT) be initiated or continued during TB treatment, as it is associated with a reduced risk of death. CPT prevents a number of infections such as pneumocystosis, toxoplasmosis, some diarrhoea and other bacterial infections (respiratory, urinary tract, etc.) and malaria.

If the patient is receiving prophylaxis against other opportunistic infections, the prophylaxis should continue during TB therapy.