See reference 1
DOT where the patient must take public transport daily or walk long distances to go to the clinic (referred to as clinic-based DOT) can actually have a negative effect. Furthermore, there can be infection control issues for the patient and staff with clinic-based DOT. Thus, home-based DOT (referred to as daily accompaniment) is preferred over clinic-base DOT when possible. Home-based DOT has been shown to be equally effective as clinic-based DOT4. DOT is usually provided by trained, supervised, and compensated treatment supporters.
The profile and the roles and responsibilities of treatment supporters for DR-TB patients are presented in Appendix 15.
Due to the duration of treatment, socio-economic support to patients is essential.