Appendix 10. Management of common adverse effects in adults on DR-TB regimens
The management of common adverse effects for first-line regimens is described in Chapter 9, Section 9.5. However, as some patients on second-line regimens are also on first-line anti-TB drugs, the first-line anti-TB drugs are also included in this appendix.
- Abdominal pain
- Alopecia
- Arthralgias
- Auditory toxicity (hearing loss)
- Depression
- Diarrhoea
- Electrolyte loss
- Fungal infection
- Gastritis
- Gynecomastia
- Haematologic abnormalities
- Hepatitis
- Hypothyroidism
- Lactic acidosis
- Metallic taste
- Nausea/vomiting
- Nephrotoxicity
- Optic neuritis
- Peripheral neuropathy
- Photosensitivity
- Psychosis
- QT prolongation
- Seizures
- Skin reactions
- Suicidal ideation
- Tendinitis/tendon rupture
- Vestibular toxicity