Appendix 8b. Former paediatric FDCs

Intensive phase

Weight
(kg)


Paediatric formulationsAdult formulations

HZR
30/150/60

E
100

E
400

H
100

EHZR
275/75/400/150

4

1 tab

1 tab




5

1 tab

1 tab




6

2 tab

1 tab




7

2 tab

1 tab




8

2 tab

2 tab




9

2 tab

2 tab




10

3 tab

2 tab




11

3 tab

2 tab




12

3 tab

2 tab




13

3 tab

2 tab




14

3 tab

2 tab




15

4 tab

3 tab




16

4 tab

3 tab




17

4 tab

3 tab




18

4 tab

3 tab




19

5 tab

3 tab




20

5 tab

1 tab



21

5 tab

1 tab



22

5 tab

1 tab



23

1 tab

2 tab

24

1 tab

2 tab

25

1 tab

2 tab

26

1 tab

2 tab

27

1 tab

2 tab

28

1 tab

2 tab

29

1 tab

2 tab


30-34

2 tab

35-39

2½ tab

40-54

3 tab

55-70

4 tab

> 70

5 tab

For example:
– A child weighing 9 kg takes 2 tablets of HZR (30 mg/150 mg/60 mg) + 2 tablets of E (100 mg) once daily.
– A child weighing 20 kg takes 5 tablets of HZR (30 mg/150 mg/60 mg) + 1 tablet of E (400 mg) once daily.

TABLETS ARE TO BE TAKEN ON A EMPTY STOMACH.

Continuation phase

Weight
(kg)


Paediatric formulation

Adult formulation

HR
30/60

HR
75/150

4

1 tab


5

1 tab


6

2 tab


7

2 tab


8

2 tab


9

2 tab


10

3 tab


11

3 tab


12

3 tab


13

3 tab


14

3 tab


15

2 tab

16

2 tab

17

2 tab

18

2 tab

19

2 tab

20

2 tab

21

2 tab

22

3 tab

23

3 tab

24

3 tab

25

3 tab

26

3 tab

27

3 tab

28

3 tab

29

3 tab


30-34

2 tab

35-39

2½ tab

40-54

3 tab

55-70

4 tab

> 70

5 tab



Daily dosing in patients < 30 kg

Daily dosing in patients ≥ 30 kg

E

15 to 25 mg/kg once daily

15 to 25 mg/kg once daily

H

7 to 15 mg/kg once daily

4 to 6 mg/kg once daily

Z

30 to 40 mg/kg once daily

20 to 30 mg/kg once daily

R

10 to 20 mg/kg once daily

8 to 12 mg/kg once daily