Appendix 5. Intravenous maintenance fluids for sick neonates

Where feasible, start IV maintenance fluids in sick neonates that need to be nil by mouth or are unable to feed sufficiently by mouth, while awaiting transfer to a neonatal care unit. 

10% glucose IV infusion: 60 to 80 ml/kg daily for ages D1 and D2
1/5 0.9% sodium chloride + 4/5 10% glucose IV infusion: 100 ml/kg daily for age D3


Birth weight/Age

D1

D2

D3

10% glucose

10% glucose

1/5 0.9% sodium chloride + 4/5 10% glucose

3500 g

9 ml/hour

12 ml/hour

15 ml/hour

3000 g - < 3500 g

8 ml/hour

11 ml/hour

13 ml/hour

2500 g - < 3000 g

7 ml/hour

9 ml/hour

11 ml/hour

2000 g - < 2500 g

5 ml/hour

7 ml/hour

9 ml/hour

Example: for a 2 day old neonate with a birth weight of 2750 g, give 10% glucose IV at 9 ml/hour, then from age D3 change to 1/5 0.9% sodium chloride + 4/5 10% glucose IV given at 11 ml/hour.