For the majority of children, careful history, clinical assessment and follow up alone are sufficient to make a diagnosis of TB, even if confirmation is not possible.
Bacteriology, chest X-ray and tuberculin skin test are useful but not essential in most cases.
A trial of treatment with anti-TB drugs is not recommended as a method to diagnose TB. The decision to treat a child should be carefully considered. Once such a decision is made, the child should be treated with a full course of therapy.