Arthralgias

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    Z, Rfb, H, Bdq, FQs
     

    Arthralgias generally diminish over time. Serum uric acid levels are frequently elevated, but this is of little clinical relevance. Anti-hyperuricaemic therapy is of no proven benefit in these patients.

     

    Begin therapy with an anti-inflammatory agent, e.g. ibuprofen PO (adult: 400 to 800 mg 3 times daily). Paracetamol PO (adult: 500 to 1000 mg 3 times daily) may also help bring relief when given together with an anti-inflammatory drug.

     

    If symptoms fail to resolve, consider lowering the dose of the suspected agent (most often Z), if this does not compromise the effectiveness of TB treatment.