Persistent pneumonia

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    Last update: November 2022


    In patients not responding to therapy, consider atypical pneumonia, tuberculosis, pneumocystosis (HIV infection and AIDS, Chapter 8).


    Bacteria responsible for atypical pneumonia are mainly Mycoplasma pneumoniae and Chlamydophila pneumoniae. If suspected, one of the following antibiotics may be used:


    First choice, azithromycin PO
    Children: 10 mg/kg (max. 500 mg) once daily for 5 days
    Adults: 500 mg on D1 then, 250 mg once daily from D2 to D5


    If not available,
    erythromycin PO
    Children: 10 mg/kg (max. 500 mg) 4 times daily for 10 to 14 days
    Adults: 500 mg 4 times daily for 10 to 14 days
    doxycycline PO (except in pregnant or breastfeeding women)

    Children under 45 kg: 2 to 2.2 mg/kg (max. 100 mg) 2 times daily for 10 to 14 days

    Children 45 kg and over and adults: 100 mg 2 times daily for 10 to 14 days