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Inform patients that they should immediately seek medical attention in the event of:
- Skin rash
- Yellowing of the skin or eyes or dark urine
- Numbness or tingling of fingers or toes
- Decreased urination
- Palpitations
- Dizziness or hearing loss
- Blurred vision, reduced visual acuity, blind spot, green-red colour blindness, eye pain, sensitivity to light
- Muscle cramps, spasms, or weakness
- Pain, burning, swelling of a tendon or muscle
- Pain or swelling in the joints
- Personality changes (e.g. depression, aggressive behaviour, anxiety)
- Severe abdominal pain, severe nausea or vomiting, black or bloody stools
- Unusual bleeding