9.7 Adverse effects

Select language:
Permalink
On this page

     

    Rapid management of adverse effects is essential to increase tolerance and improve outcomes.

    • In the event of minor adverse effects, drugs should not be stopped. Providing support and using ancillary medicines is all that is necessary.
    • In the event of major adverse effects, the regimen may need to be adapted.

     

    Table 9.5  Main adverse effects and likely responsible drugs

     

    Adverse effects

    Drug(s) likely responsible

    Management

    Minor

    Nausea, vomiting

    Eto, Z

    Appendix 17

    Arthralgia

    Z

    Appendix 17

    Peripheral neuropathy

    H, Eto

    Appendix 17

    Orange/red urine, tears, etc.

    R, P

    Patients should be told before starting treatment that this is normal.

    Major

    Skin reactions

    E, Z, R, H, P, Mfx, Eto

    Appendix 17

    Hepatotoxicity

    Z, H, R, P, Eto

    Appendix 17

    Optic neuritis

    E

    Appendix 17

    Haematologic disorders

    R, P, H, E

    Appendix 17

     

    For more information on individual drugs, see Appendix 10.