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Update: October 2022
Forms and strengths
- 200 mg tablet
Dosage
- Adolescent 15 years and over and adult: 200 mg once daily, in combination with :
- bedaquiline, linezolid and moxifloxacin (BPaLM)
- bedaquiline, linezolid and clofazimine (BPaLC)
- bedaquiline and linezolid (BPaL)
- Maximum dose: 200 mg daily
|
Age |
Daily dose (mg) |
200 mg tablet |
|---|---|---|
|
< 15 years |
Do not administer |
− |
|
≥ 15 years |
200 |
1 |
Contra-indications, adverse effects, precautions
- Do not administer if one of the drugs included in the regimen is contraindicated.
- The contribution of pretomanid to the adverse effects of pretomanid-containing regimens is not determined.
- For adverse effects of companion drugs, see individual drug information sheets.
- Pregnancy: use if benefits outweigh the risks (safety not established).
- Breastfeeding: avoid breastfeeding during treatment (safety not established).
Monitoring
- Symptomatic monitoring.
-
For monitoring of companion drugs, see individual drug information sheets.
Patient instructions
- Take with food.
Storage
–
–
Below 25 °C