SODIUM CHLORIDE 0.9% = NaCl

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    Indications

    • Vehicle for the administration of parenteral drugs
    • Fluid replacement

    Forms and strengths

    • 100 ml, 250 ml, 500 ml and 1000 ml bottles or bags

    Composition

    • Isotonic solution of sodium chloride (0.9 g per 100 ml) for infusion
    • Ionic composition:

    sodium (Na+)   150 mmol  (150 mEq) per litre

    chloride (Cl)   150 mmol  (150 mEq) per litre

    Contra-indications, adverse effects, precautions

    • Use with caution in patients with hypertension, heart failure, oedema, ascites due to cirrhosis, renal impairment and other conditions associated with sodium retention.
    • May cause: pulmonary oedema in the event of too rapid infusion or infusion of excessive amounts.
    • Do not use as vehicle for the administration of amphotericin B (incompatibility): use only 5% glucose solution.

    Remarks

    • For correction of hypovolaemia due to haemorrhage, administer 3 times the lost volume only if:
      • blood loss does not exceed 1500 ml in adults;
      • cardiac and renal function are not impaired.
    • 0.9% sodium chloride solution may be used to prevent hypotension induced by spinal anaesthesia.
    • This solution contains neither potassium nor lactate. In case of severe dehydration, use Ringer Lactate. If Ringer Lactate is not available, add KCl (2 g/l) + NaCl (4 g/l) to 5% glucose.
    • For external use: sterile 0.9% sodium chloride solution is used for cleansing of non-infected wounds, wound irrigation, eye cleansing (conjunctivitis, eye irrigations), nasal lavage in the event of obstruction, etc.

    Storage

    Below 25 °C