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- Vehicle for the administration of parenteral drugs
- Fluid replacement
Forms and strengths
- 100 ml, 250 ml, 500 ml and 1000 ml bottles or bags
- Isotonic solution of sodium chloride (0.9 g per 100 ml) for infusion
- Ionic composition:
sodium (Na+) 150 mmol (150 mEq) per litre
chloride (Cl–) 150 mmol (150 mEq) per litre
Contra-indications, adverse effects, precautions
- Use with caution in patients with hypertension, heart failure, oedema, ascites due to cirrhosis, renal impairment and other conditions associated with sodium retention.
- May cause: pulmonary oedema in the event of too rapid infusion or infusion of excessive amounts.
- Do not use as vehicle for the administration of amphotericin B (incompatibility): use only 5% glucose solution.
- For correction of hypovolaemia due to haemorrhage, administer 3 times the lost volume only if:
- blood loss does not exceed 1500 ml in adults;
- cardiac and renal function are not impaired.
- 0.9% sodium chloride solution may be used to prevent hypotension induced by spinal anaesthesia.
- This solution contains neither potassium nor lactate. In case of severe dehydration, use Ringer Lactate. If Ringer Lactate is not available, add KCl (2 g/l) + NaCl (4 g/l) to 5% glucose.
- For external use: sterile 0.9% sodium chloride solution is used for cleansing of non-infected wounds, wound irrigation, eye cleansing (conjunctivitis, eye irrigations), nasal lavage in the event of obstruction, etc.
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