– Vehicle for the administration of parenteral drugs
– Fluid replacement

Forms and strengths

– 100 ml, 250 ml, 500 ml and 1000 ml bottles or bags


– Isotonic solution of sodium chloride (0.9 g per 100 ml) for infusion

– Ionic composition:

sodium (Na+)    150 mmol (150 mEq) per litre
chloride (Cl)    150 mmol (150 mEq) per litre

Contra-indications, adverse effects, precautions

– Use with caution in patients with hypertension, heart failure, oedema, ascites due to cirrhosis, renal impairment and other conditions associated with sodium retention.
– May cause: pulmonary oedema in the event of too rapid infusion or infusion of excessive amounts.
– Do not use as vehicle for the administration of amphotericin B (incompatibility): use only 5% glucose solution.


– For correction of hypovolaemia due to haemorrhage, administer 3 times the lost volume only if:
• blood loss does not exceed 1500 ml in adults;
• cardiac and renal function are not impaired.
– 0.9% sodium chloride solution may be used to prevent hypotension induced by spinal anaesthesia.
– This solution contains neither potassium nor lactate. In case of severe dehydration, use Ringer Lactate. If Ringer Lactate is not available, add KCl (2 g/l) + NaCl (4 g/l) to 5% glucose.
– For external use: sterile 0.9% sodium chloride solution is used for cleansing of non-infected wounds, wound irrigation, eye cleansing (conjunctivitis, eye irrigations), nasal lavage in the event of obstruction, etc.
Storage: below 25 °C