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    • Prevention of cholera in epidemic, endemic or humanitarian emergency contexts

    Composition, forms, route of administration

    • Inactivated whole cell bivalent vaccine containing Vibrio cholerae O1 (serotypes Inaba and Ogawa, and biotypes classical and El Tor) and Vibrio cholerae O139
    • Oral suspension, 1.5 ml in monodose plastic tube. DO NOT ADMINISTER BY PARENTERAL ROUTE.

    Dosage and vaccination schedule

    • Child 1 year and over and adult: 2 doses of 1.5 ml administered at least 14 days apart
    • In certain contexts (e.g. outbreak and limited number of vaccines), a single dose of 1.5 ml is administered.
    • Shake the vial, squirt the entire contents of the vial into the mouth.


    For young children, the contents of the vial can be drawn up in a syringe and squirted into the mouth.

    Contra-indications, adverse effects, precautions

    • Do not administer to children less than one year.
    • Do not administer in the event of hypersensitivity to any component of the vaccine or history of an allergic reaction to a previous dose.
    • Vaccination should be postponed in the event of severe acute febrile illness; minor infections are not contra-indications.
    • May cause: nausea, vomiting, abdominal cramping, diarrhoea.
    • Drinking water after swallowing the vaccine may reduce its unpleasant taste and prevent vomiting. If the patient vomits the dose of vaccine, wait for 10 minutes and re-administer the same dose and follow with a larger volume of water.
    • Pregnancy: can be administered (the benefits outweigh the risks).
    • Breast-feeding: no contra-indication


    • Immunity develops one week after administration and lasts up to 6 months after a single dose and at least 3 years after 2 doses.


    –  Between 2 °C and 8 °C. Do not freeze; discard if vaccine has been frozen.
    Shanchol® vaccines used in controlled temperature chain (CTC) can be stored at temperatures of up to 40 °C for 14 days maximum. All vaccines removed from the cold chain and not used within 14 days or exposed to temperatures > 40 °C must be discarded.