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    • Prevention of invasive infections, pneumonia and acute otitis media due to Streptococcus pneumoniae, in children from 6 weeks of age

    Composition, forms, route of administration

    • 10 or 13 valent pneumococcal polysaccharide conjugate vaccine 
    • Suspension for injection:
      • 10 valent vaccine: in multidose vials
      • 13 valent vaccine: in monodose and multidose vials
    • For IM injection into the anterolateral part of the thigh in children < 2 years and into the deltoid muscle in children ≥ 2 years. 

    Dosage and vaccination schedule

    • Child: 0.5 ml per dose
    • Child from 6 weeks to < 12 months:
      • 3p+0 schedule
        3 doses 4 weeks apart at 6, 10 and 14 weeks of age 
      • 2p+1 schedule
        2 doses 8 weeks apart and a booster dose between 9 and 15 months
    • Child from 12 months to < 2 years: 2 doses 8 weeks apart
    • Child from 2 to 5 years: a single dose

    Contra-indications, adverse effects, precautions

    • Do not administer in the event of allergic reactions to a previous dose of vaccine.
    • Vaccination should be postponed in the event of severe acute febrile illness; minor infections are not contra-indications.
    • May cause: mild local reactions (redness and pain at the injection site), fever, irritability, drowsiness, loss of appetite; rarely: seizures, anaphylactic reactions.
    • If administered simultaneously with other vaccines, use different syringes and injection sites.


    • If the vaccination is interrupted before the complete series has been administered, continue the vaccination schedule from where it was interrupted, do not repeat administration of the previous dose.
    • Choice of vaccines and vaccination schedule: follow national recommendations.
    • Shake before use to homogenise the vaccine.


    –  Between 2 °C and 8 °C. Do not freeze.
    • 10 valent vaccine, 2 dose vial: if open vial is not used entirely within 6 hours it should be discarded.
    • 10 and 13 valent vaccine, 4 dose vial: if open vial is not entirely used it can be stored for 28 days, providing the cold chain is respected.