– Prevention of gastroenteritis due to rotavirus infection in infants

Composition, forms, route of administration

– Live-attenuated monovalent human rotavirus vaccine (RV1, strain RIX4414, Rotarix®)
– Oral suspension, 1.5 ml in monodose plastic tube. DO NOT ADMINISTER BY PARENTERAL ROUTE.

Dosage and vaccination schedule

– Child from 6 weeks to 24 months: 2 doses at least 4 weeks apart. It is recommended to administer the 1st dose at 6 weeks of age and the 2nd dose at 10 weeks of age, at the same time as the first 2 doses of pentavalent vaccine (diphtheria, tetanus, pertussis, hepatitis B and Haemophilus influenzae).
– Shake the plastic tube, squeeze the entire content of the tube into the mouth.

Contra-indications, adverse effects, precautions

– Do not administer in case of acute gastroenteritis, history of intussusception, severe immunodeficiency.
– Do not administer in the event of allergic reactions to a previous dose of vaccine.
– Vaccination should be postponed in the event of severe acute febrile illness; minor infections are not contra-indications.
– May cause: diarrhoea,abdominal pain, irritability; rarely: intussusception, anaphylactic reactions.
– If the patient vomits the dose of vaccine, wait a few minutes and re-administer the same dose.


– Also comes in a monovalent human vaccine (RV1, strain 116E, Rotavac®) and pentavalent human-bovine vaccine (RV5), to be administered in 3 doses 4 week apart. 
– Rotavirus vaccine can be administered concomitantly with oral polio vaccine (OPV).
– Storage: between 2 °C and 8 °C. Do not freeze -