METAMIZOLE = DIPYRONE = NORAMIDOPYRINE injectable

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    Prescription under medical supervision

     

     
    Given the potentially serious adverse effects and that safer alternatives exist, this drug should not be prescribed as first choice treatment.

     

    Therapeutic action

    • Analgesic, antipyretic

    Indications

    • Pain, fever

    Forms and strengths, route of administration

    • 1 g in 2 ml ampoule (500 mg/ml) for IM, SC or slow IV injection or infusion

    Dosage

    • Adult: 500 mg every 8 hours if necessary

    Duration

    • As short as possible.

    Contra-indications, adverse effects, precautions

    • May cause:
      • severe agranulocytosis, potentially fatal, regardless of dose or duration of treatment; 
      • allergic reactions, anaphylactic shock.
    • Pregnancy: CONTRA-INDICATED
    • Breast-feeding: CONTRA-INDICATED

    Remarks

    • Metamizole is not included in the WHO list of essential medicines.

    Storage

    Below 25 °C