METAMIZOLE = DIPYRONE = NORAMIDOPYRINE oral

Prescription under medical supervision

Given the potentially serious adverse effects and that safer alternatives exist, this drug should not be prescribed as first choice treatment.


Therapeutic action

– Analgesic, antipyretic

Indications

– Pain, fever

Forms and strengths

– 500 mg tablet

Dosage

– Adult: 500 mg to 1 g 2 to 3 times daily 

Duration

– As short as possible.

Contra-indications, adverse effects, precautions

– May cause:
• severe agranulocytosis, potentially fatal, regardless of dose or duration of treatment; 
• allergic reactions, anaphylactic shock.

– PregnancyCONTRA-INDICATED
– Breast-feedingCONTRA-INDICATED

Remarks

– Metamizole is not included in the WHO list of essential medicines.
  Storage: below 25 °C