PODOPHYLLOTOXIN 0.5%, solution or gel

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    Prescription under medical supervision

     

    Therapeutic action

    • Antiviral, antimitotic, cytolytic agent active against human papillomaviruses (HPVs)

    Indications

    • External genital warts, perianal warts and vaginal warts

    Forms and strengths

    • 0.5% solution or gel, with applicator tips

    Dosage

    • One application to warts 2 times daily  
    • For vaginal warts, allow to dry before removing the speculum.

    Duration

    • 3 consecutive days per week, for a maximum of 4 weeks

    Contra-indications, adverse effects, precautions

    • Do not use to treat genital warts in children.
    • Do not apply to warts > 3 cm.
    • Do not apply to cervical, urethral, anorectal or oral warts.
    • Do not apply to healthy skin.
    • May cause local reactions: erythema, ulceration, pain in area where applied.
    • Use a new applicator tip for each application.
    • Avoid contact with eyes. In case of eye contact flush immediately with plenty of water.
    • Pregnancy: CONTRA-INDICATED
    • Breast-feeding: CONTRA-INDICATED

    Remarks

    • When treatment is contra-indicated or has failed after 4 weeks, change treatment method (cryosurgery, electrosurgery, surgical removal).

    Storage

     
    –  Below 25 °C