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- Case definitions, triage and treatment
- Uncomplicated cases (outpatient treatment)
- Standard treatment
- Treatment of complications
- Complicated cases (inpatient treatment)
- Standard treatment
- Respiratory and ENT complications
- Ocular complications
- Gastrointestinal complications
- Other complications
- If the patient is to be transferred to a hospital
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Case definitions, triage and treatment
Uncomplicated cases (outpatient treatment)
Standard treatment
- Paracetamol PO: 20 mg/kg 3 times daily
Age < 2 months 2-11 months 1-4
years
5-10 years 11-15 years Adult Weight < 5 kg 5-9 kg 10-17 kg 18-32 kg 33-47 kg Oral sol. 120 mg/5 ml 3 ml
x 3
4 to 10 ml
x 3
– – – – 100 mg tab 3/4 tab
x 3
1 to 2 tab
x 3
2 to 3 tab
x 3
– – – 500 mg tab – – ½ tab
x 3
½ to 1 tab
x 3
1½ to 2 tab
x 3
2 tab
x 3
- Amoxicillin PO: 25 to 50 mg/kg 2 times daily for 5 days in children under 5 years
Age < 2 months 2-11 months 1-4 years Weight < 5 kg 5-9 kg 10-17 kg Oral susp. 125 mg/5 ml ½ tsp x 2 2 to 3 tsp x 2 – 250 mg tab 1 tab x 2 1 to 2 tab x 2 2 to 3 tab x 2 500 mg tab – – 1 to 2 tab x 2
- Retinol* (vitamin A) PO: one dose on Day1
Age < 6 months 6-11 months 1 year and over Weight < 7.5 kg 7.5-9 kg 10 kg and over Dose 50 000 IU 100 000 IU 200 000 IU 200 000 IU capsule
(8 drops)2 drops 4 drops 1 capsule
* except in pregnant women
- Wipe eyes with cotton and clean water.
- Keep nasal passages clear (using a tissue or by nasal lavage with 0.9% sodium chloride if appropriate).
- Depending on the context, for children < 3 or 5 years, food supplement: 500 kcal daily, ready-to use food, 2 weeks.
Treatment of complications
- Pneumonia without severe signs or acute otitis media: amoxicillin PO 5 days
- Purulent conjunctivitis: clean the eyes with clean water + tetracycline eye ointment 1% (2 times daily, 7 days)
- Bitot’s spots: retinol PO one dose on Day1, Day2, Day8
- Oral candidiasis: nystatin 100 000 IU/ml oral suspension (1 ml 4 times daily, 7 days)aCitation a.If not available, 0.25% gentian violet, applied 2 times/day for 5 days maximum.
- Diarrhoea without dehydration: WHO plan A
|
Complicated cases (inpatient treatment)
Standard treatment
- Paracetamol PO: 20 mg/kg 3 times daily
Age < 2 months 2-11 months 1-4
years
5-10
years
11-15
years
Adult Weight < 5 kg 5-9 kg 10-17 kg 18-32 kg 33-47 kg Oral sol. 120 mg/5 ml 3 ml
x 3
4 to 10 ml
x 3
– – – – 100 mg tab 3/4 tab
x 3
1 to 2 tab
x 3
2 to 3 tab
x 3
– – – 500 mg tab – – ½ tab
x 3
½ to 1 tab
x 3
1½ to 2 tab
x 3
2 tab
x 3
- Only in case of high fever in a child who is vomiting repeatedly or whose consciousness is impaired, paracetamol IV, 500 mg vial (10 mg/ml, 50 ml
Weight < 10 kg 10-50 kg > 50 kg Dose to be administered
every 6 hours (in mg)7.5 mg/kg 15 mg/kg 1 g Dose to be administered
every 6 hours (in ml)0.75 ml/kg 1.5 ml/kg 100 ml Dose maximum 30 mg/kg/day 60 mg/kg/day 4 g/day
Administer paracetamol IV in 4 doses at 6-hour intervals. Each dose is administered over 15 minutes. Change to oral route as soon as possible.
- Amoxicillin PO: 25 to 50 mg/kg 2 times daily for 5 days in children under 5 years
Age < 2
months
2-11
months
1-4
years
5-10
years
11-15
years
Adult Weight < 5 kg 5-9 kg 10-17 kg 18-32 kg 33-47 kg Oral susp. 125 mg/5 ml
1½ tsp
x 2
2 to 3 tsp
x 2
– – – – 250 mg tab 1 tab
x 2
1 to 2 tab
x 2
2 to 3 tab
x 2
– – – 500 mg tab – – 1 to 2 tab
x 2
2 to 3 tab
x 2
3 to 4 tab
x 2
4 tab
x 2
- Retinol (vitamin A) PO: one dose on Day1 and Day2
Age < 6 months 6-11 months 1 year and over Weight < 7.5 kg 7.5-9 kg 10 kg and over Dose 50 000 IU 100 000 IU 200 000 IU 200 000 IU capsule (8 drops) 2 drops 4 drops 1 capsule
Administer retinol PO in 2 doses (Day1, Day2) to all patients except:
- pregnant women (contra-indicated);
- in the event of corneal lesions or Bitot’s spots (in this case, give 3 doses, on Day1, Day2, Day8).
- Wipe eyes with clean water 2 times daily.
- Keep nasal passages clear (using a tissue or by nasal lavage with 0.9% sodium chloride if appropriate).
- Give caloric food, smaller, more frequent meals or breastfeed more frequently.
- Make the child drink regularly.
- Depending on the context, for children < 3 or 5 years, food supplement: 500 kcal daily, ready-to use food, 2 weeks.
Respiratory and ENT complications
Severe pneumonia
- Oxygen if cyanosis or SpO2 < 90%
- Ceftriaxone slow IV or IM (1 g to be dissolved in 5 ml): 100 mg/kg once daily
Age 1-11
months
1-4
years
5-10
years
11-15
years
Adult Weight 4-9 kg 10-17 kg 18-32 kg 33-47 kg Dose 400 to 900 mg 1 to 1.5 g 2 to 3 g 3 to 4 g 4 g Volume to be injected
(1 g vial /5 ml of diluent)2 to 5 ml 1 to 1½ vial 2 to 3 vials 3 to 4 vials 4 vials
PLUS
- Cloxacillin IV infusion over 60 minutes (500 mg to be dissolved in 5 ml water for injection): 25 to 50 mg/kg every 6 hours
Age < 2
months
2-11
months
1-4
years
5-10
years
11-15
years
Adult Weight < 5 kg 5-9 kg 10-17 kg 18-32 kg 33-47 kg Dose 200 mg
x 4
250 to 400 mg
x 4
500 to 750 mg
x 4
1 g
x 4
1.5 g
x 4
2 g
x 4
Volume to be injected
(500 mg vial /5 ml)2 ml
x 4
2.5 to 4 ml
x 4
1 to 1½ vial
x 4
2 vials
x 4
3 vials
x 4
4 vials
x 4
Parenteral treatment for at least 3 days then, once the child no longer has fever or clinical signs of severe infection, change to amoxicillin/clavulanic acid PO: 40 mg/kg 2 times daily to complete 7 to 10 days of treatment
Age |
< 2 months |
2-11 months |
1-4 years |
5-10 years |
11-15 years |
Adult |
---|---|---|---|---|---|---|
Weight | < 5 kg | 5-9 kg | 10-17 kg | 18-32 kg | 33-47 kg | |
Oral susp. 100 + 12.5 mg/5 ml |
8 ml x 2 |
12 ml x 2 |
– |
– | – | – |
500/62,5 mg tab | – | – |
1 tab x 2 |
2 tab x 2 |
3 tab x 2 |
3 tab x 2 |
Pneumonia (without signs of severity)
- Amoxicillin PO: 25 to 50 mg/kg 2 times daily for 5 days
Age < 2
months
2-11
months
1-4
years
5-10
years
11-15
years
Adult Weight < 5 kg 5-9 kg 10-17 kg 18-32 kg 33-47 kg Oral susp. 125 mg/5 ml
1½ tsp
x 2
2 to 3 tsp
x 2
– – – – 250 mg tab 1 tab
x 2
1 to 2 tab
x 2
2 to 3 tab
x 2
– – – 500 mg tab – – 1 to 2 tab
x 2
2 to 3 tab
x 2
3 to 4 tab
x 2
4 tab
x 2
As a second line (treatment failure after 48 hours), amoxicillin/clavulanic acid PO: 40 mg/kg 2 times daily for 7 days (see Severe pneumonia).
Acute otitis media
- Amoxicillin PO: 25 to 50 mg/kg 2 times daily for 5 days (see above)
- If there is discharge from the ear, keep the ear clean by wiping the external auditory canal with dry cotton wool.
Severe laryngotracheobronchitis (croup)
- Dexamethasone (1 ml ampoule, 4 mg/ml) IM: 0.6 mg/kg single dose
Age < 2 months 2-11 months 1-4 years 3-4 years Weight < 5 kg 5-9 kg 10-13 kg 14-17 kg Dose 2 mg 4 mg 8 mg 10 mg Volume to be injected 0.5 ml 1 ml 2 ml 2.5 ml
- Nebulized epinephrine (1 mg ampoule, 1 mg/ml): 0.5 ml/kg per dose
Age 1
month
2
months
3
months
4-6 months 7-9 months 10-11 months 1-4 years* Weight 4.5 kg 5 kg 6 kg 7 kg 8 kg 9 kg 10-17 kg Epinephrine
(1 mg/ml ampoule)2 ml 2.5 ml 3 ml 3.5 ml 4 ml 4.5 ml 5 ml 0.9% NaCl to be added 2 ml 2 ml 1 ml 1 ml – – –
* In children > 4 years or > 17 kg, the dose should not exceed 5 ml.
- Oxygen if cyanosis or SpO2 < 90%
Ocular complications
Corneal lesions (opacification, ulcer)
- Retinol (vitamin A) PO: one dose on Day1, Day2, Day8
Age < 6 months 6-11 months 1 year and over Weight < 7.5 kg 7.5-9 kg 10 kg and over Dose 50 000 IU 100 000 IU 200 000 IU 200 000 IU capsule (8 drops) 2 drops 4 drops 1 capsule
- Tramadol PO if ocular pain:
- Child over 12 years and adult: 50 to 100 mg every 6 hours (max. 400 mg daily)
Age > 12 years Adult Dose 50 mg x 4 100 mg x 4 Gél 50 mg 1 cap x 4 2 cap x 4
- Child over 12 years and adult: 50 to 100 mg every 6 hours (max. 400 mg daily)
- Keep the eye clean: clean with 0.9% sterile sodium chloride and apply tetracycline eye ointment 1%, 2 times daily, to prevent or treat bacterial superinfection.
- Protective dressing as long there is photophobia.
Bitot’s spots
- Retinol (vitamin A) PO: one dose on Day1, Day2 and Day8, as above
Purulent conjunctivitis
- Clean the eyes with clean water 2 times daily.
- Tetracycline eye ointment 1%: one application 2 times daily for 7 days
Gastrointestinal complications
Oral candidiasis
- Nystatin PO: 1 ml of oral suspension (100 000 IU) 4 times daily for 7 daysbCitation b.If not available, 0.25% gentian violet, applied 2 times/day for 5 days maximum. . If there is no improvement after 3 days, increase the dose to 200 000 IU 4 times daily.
Diarrhoea without dehydration
WHO treatment plan A
Diarrhoea with dehydration
- Rehydration:
Moderate (some) dehydration: WHO treatment plan B
Severe dehydration: WHO treatment plan C
+
- Zinc sultate (20 mg dispersible tablet):
- Child under 6 months: 10 mg once daily for 10 days (= ½ tab daily)
- Child from 6 months to 5 years: 20 mg daily for 10 days (= 1 tab daily)
In infants: place ½ or 1 tablet in a teaspoon and add a bit of water to dissolve it.
In children over 2 years: tablets may be chewed or dissolved.
Ask the parents not to remove the tablets from the blister-pack. Once a tablet is removed from the blister-pack, it must be administered immediately.
Other complications
Acute malnutrition
Follow the protocol for managing malnutrition (RTUF).
Seizures
Generalised seizure lasting > 3 minutes:
- diazepam: 10 mg ampoule (5 mg/ml, 2 ml)
Child: 0.5 mg/kg rectally, without exceeding a total dose of 10 mg
- For intrarectal administration, use a 1 ml-syringe graduated in 0.01 ml (with no needle). Introduce the tip of the syringe into the rectum (1.5 to 4 cm depending on age).
Age < 4 months 4-11 months 1-2 years Weight < 7 kg 7-9 kg 10-13 kg Dose in mg
2.5 mg 4 mg 6 mg Volume to be administered 0.5 ml 0.8 ml 1.2 ml
If seizures persist after 5 minutes after the first dose, repeat the same dose once.
If the patient is to be transferred to a hospital
- Administer the first dose of amoxicillin PO and paracetamol PO.
- Severe dehydration: place a IV line and transfer the patient when stable.
- Moderate (some) dehydration: the patient should be able to drink ORS while being transferred.
- Corneal lesion: protect the eye with a dry dressing.
- Send the patient with a transfer form indicating the reason for the referral and treatments administered.