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    Last updated: February 2024


    Prescription under medical supervision


    Do not exceed the recommended dose and duration of treatment (risk of serious neurological adverse effects).


    Therapeutic action

    • Antiemetic (dopamine antagonist)


    • Symptomatic treatment of nausea and vomiting in adults

    Forms and strengths

    • 10 mg tablet


    • Adult under 60 kg: 5 mg 3 times daily
    • Adult over 60 kg: 10 mg 3 times daily


    The interval between each dose should be at least 6 hours (even in the event of vomiting).


    • Max. 5 days

    Contra-indications, adverse effects, precautions

    • Do not administer to children < 18 years and to patients with gastrointestinal haemorrhage, obstruction or perforation.
    • Reduce the dose by half in patients with severe renal impairment.
    • Administer with caution and monitor use in patients > 60 years and patients with epilepsy or Parkinson's disease.
    • May cause: drowsiness (caution when driving/operating machinery), dizziness, confusion, extrapyramidal symptoms, seizures (especially in patients with epilepsy), allergic reactions; neuroleptic malignant syndrome (unexplained hyperthermia with neuromuscular disorders), exceptional but requiring immediate treatment discontinuation.
    • Do not combine with levodopa (antagonism).
    • Avoid combination with CNS depressants (opioid analgesics, antipsychotics, sedatives, antidepressants, antihistamines, etc.).
    • Avoid alcohol during treatment (increased risk of adverse effects).
    • Pregnancy: no contra-indication
    • Breast-feeding: no contra-indication


    –  Below 25 °C