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Therapeutic action
- Short-acting beta-2 agonist bronchodilator
Indications
- Symptomatic treatment of asthma attack
Forms and strengths
- Solution or suspension for inhalation in pressurised metered dose inhaler, delivering 100 micrograms of salbutamol/puff
Dosage and duration
Asthma attack
- Child and adult: 2 to 10 puffs (200 to 1000 micrograms) every 20 minutes for the first hour
Then:
- If the attack is completely resolved: 2 to 4 puffs (200 to 400 micrograms) every 4 to 6 hours for 24 to 48 hours
- If the attack is not completely resolved: 2 to 10 puffs (200 to 1000 micrograms) every 1 to 4 hours until symptoms subside then 2 to 4 puffs (200 to 400 micrograms) every 4 to 6 hours for 24 to 48 hours
Chronic asthma (when symptomatic only)
- Child and adult: 2 to 4 puffs (200 to 400 micrograms) up to 4 times daily if necessary
Administration technique
- Shake the inhaler. Remove the mouthpiece cover.
- Breathe in and breathe out as completely as possible. Place the lips tightly around the mouthpiece. Inhale deeply while activating the inhaler. Hold breath 10 seconds before exhaling.
- Hand-breath co-ordination is very difficult in children under 6 years, older patients and patients with severe dyspnoea. Use a spacer to facilitate administration and improve the efficacy of treatment.
Contra-indications, adverse effects, precautions
- May cause: headache, tremor and tachycardia, hyperglycaemia; hypokalaemia (after high doses).
- Pregnancy: no contra-indication
- Breast-feeding: no contra-indication
Remarks
- In severe asthma attack, preferably administer salbutamol by nebulisation, in combination with ipratropium. Use salbutamol metered dose inhaler only if nebuliser solution is not available.
- Salbutamol is also used for other conditions associated with bronchoconstriction (e.g. chronic obstructive pulmonary disease, some severe respiratory infections).
- Clean the mouthpiece before and after each use.
- Do not pierce or incinerate used aerosol containers (risk of explosion).
Storage
– Below 25 °C