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    Prescription under medical supervision


    Therapeutic action

    • Phosphonic acid derivative antibacterial


    • Acute uncomplicated cystitis in women, without fever nor flank pain
    • Asymptomatic bacteriuria in pregnant women

    Forms and strengths

    • Granules for oral solution in 3 g sachet, to be dissolved in filtered water

    Dosage and duration

    • 3 g single dose

    Contra-indications, adverse effects, precautions

    • Do not administer to patients with severe renal impairment, allergy to fosfomycin.
    • May cause: gastrointestinal disturbances, skin rash; rarely, allergic reactions.
    • Pregnancy: no contra-indication
    • Breast-feeding: no contra-indication


    • In the treatment of cystitis, symptoms should improve within 3 days of treatment. If not, the patient should consult again. Treatment failure may be due to the presence of naturally fosfomycin-resistant organisms (Staphylococcus saprophyticus).
    • Take between meals or at bedtime (food decreases absorption).
    • Fosfomycin is not included in the WHO list of essential medicines.


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