LOPERAMIDE oral

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    Prescription under medical supervision

     

    Therapeutic action

    • Opioid antidiarrhoeal

    Indications

    • Symptomatic treatment of persistent diarrhoea in HIV patients, in combination with rehydration

    Forms and strengths

    • 2 mg capsule or tablet
    • Also comes in 1 mg/5 ml oral solution.

    Dosage

    • Child from 2 to 5 years: 1 mg 3 times daily
    • Child from 6 to 8 years: 2 mg 2 times daily
    • Child over 8 years: 2 mg 3 times daily

     

    Age

    Weight

    0-2 years

    < 13 kg

    2-5 years

    13 - 20 kg

    6-8 years

    20 - 30 kg

    > 8 years

    > 30 kg

    Oral solution

    Do not
    administer

    1 tsp x 3

    2 tsp x 2

    2 tsp x 3

    Capsule

    –

    1 cap x 2

    1 cap x 3

     

    • Adult: 4 mg (2 capsules), then 2 mg (1 capsule) after each loose stool, without exceeding 16 mg daily (8 capsules daily)

    Duration

    • According to clinical response

    Contra-indications, adverse effects, precautions

    • Do not exceed indicated doses.
    • Do not administer to children under 2 years.
    • Do not administer to patients with bloody diarrhoea, acute inflammatory bowel disease, diarrhoea due to antibiotics.
    • May cause: constipation, allergic skin reactions, drowsiness, dizziness.
    • In the event of overdosage, treat with naloxone.
    • Pregnancy: no contra-indication
    • Breast-feeding: no contra-indication

    Remarks

    • Rehydration is essential and must be adapted to the severity of diarrhoea.
    • Loperamide is not included in the WHO list of essential medicines.

    Storage

     
    - Below 25 °C 
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