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- Third-generation cephalosporin antibacterial
- Typhoid fever
- Acute cystitis in girls over 2 years, pregnant women and lactating women
- Acute pyelonephritis in adults
- Cervicitis and urethritis due to Neisseria gonorrhoeae (in combination with a treatment for chlamydia)
- Second-line treatment of shigellosis
Forms and strengths
- 200 mg tablet
- 100 mg/5 ml powder for oral suspension, to be reconstituted with filtered water
- Child: 10 mg/kg (max. 200 mg) 2 times daily
- Adult: 200 mg 2 times daily
Acute cystitis in girls over 2 years and shigellosis
- Child: 8 mg/kg (max. 400 mg) once daily
- Adult: 400 mg once daily
Acute cystitis in pregnant and lactating women, acute pyelonephritis in adult
- 200 mg 2 times daily
Cervicitis and urethritis due to Neisseria gonorrhoeae
- Child: 8 mg/kg (max. 400 mg) single dose
- Adult: 400 mg single dose
- Typhoid fever and acute pyelonephritis: 10 to 14 days
- Acute cystitis: 3 days for girls and 5 days for adults
- Shigellosis: 5 days
Contra-indications, adverse effects, precautions
- Do not administer to patients with allergy to cephalosporins.
- Administer with caution to penicillin-allergic patients (cross-sensitivity may occur) and in patients with severe renal impairment (reduce dosage).
- May cause: gastrointestinal disturbances (especially diarrhoea), headache, dizziness, allergic reactions (rash, pruritus, fever). In the event of allergic reaction, stop treatment immediately.
- Pregnancy: no contra-indication
- Breast-feeding: no contra-indication
– Below 25 °C
For the oral suspension (powder or reconstituted suspension): follow manufacturer’s instructions.