NICLOSAMIDE oral

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Therapeutic action

  • Anthelminthic (taenicide)

Indications

  • Taeniasis: beef tapeworm (Taenia saginata), pork tapeworm (Taenia solium), dwarf tapeworm (Hymenolepis nana) and fish tapeworm (Diphyllobothrium latum)

Forms and strengths

  • 500 mg chewable tablet

Dosage and duration

T. saginata, T. solium and D. latum

  • Child under 2 years: 500 mg single dose
  • Child from 2 to 6 years: 1 g single dose
  • Child over 6 years and adult: 2 g single dose
     

H. nana

  • Child under 2 years: 500 mg on D1, then 250 mg once daily for 6 days
  • Child from 2 to 6 years: 1 g on D1, then 500 mg once daily for 6 days
  • Child over 6 years and adult: 2 g on D1, then 1 g once daily for 6 days

Contra-indications, adverse effects, precautions

  • May cause: gastrointestinal disturbances.
  • Pregnancy: no contra-indication
  • Breast-feeding: no contra-indication

Remarks

  • Chew or crush the tablets before swallowing with water.
  • In the event of vomiting, the single dose may be divided in 2 doses taken with an interval of one hour.
  • As niclosamide is a taenicide not a taenifuge, do not expect the patient to expel the worm, portions are voided in a partially digested form.
  • Niclosamide is not active against the larval form of T. solium (cysticercosis).

Storage

 
– Below 25 °C