LOPERAMIDE oral

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    Last updated: January 2024

     

    Prescription under medical supervision

     

    Therapeutic action

    • Opioid antidiarrhoeal

    Indications

    • Symptomatic treatment of persistent diarrhoea in adults with HIV infection, in combination with rehydration

    Forms and strengths

    • 2 mg capsule or tablet

    Dosage

    • Adult: 4 mg (2 capsules), then 2 mg (1 capsule) after each loose stool, without exceeding 16 mg daily (8 capsules daily).

    Duration

    • According to clinical response

    Contra-indications, adverse effects, precautions

    • Do not exceed indicated doses.
    • Do not administer to children.
    • Do not administer to patients with bloody diarrhoea, ulcerative colitis, diarrhoea due to antibiotics.
    • May cause: constipation, allergic skin reactions, drowsiness, dizziness.
    • In the event of overdosage, treat with naloxone.
    • Pregnancy: no contra-indication
    • Breast-feeding: no contra-indication

    Remarks

    • Rehydration is essential and must be adapted to the severity of diarrhoea.
    • Loperamide is not included in the WHO list of essential medicines.

    Storage

     
    –  Below 25 °C