LORATADINE oral

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    Last updated: February 2024

     

    Prescription under medical supervision

     

    Therapeutic action

    •  H1 antihistamine

    Indications

    • Symptomatic treatment of minor allergic reactions (urticaria, allergic conjunctivitis, etc.)

    Forms and strengths

    • 5 mg/5 ml oral solution
    • 10 mg tablet

    Dosage

    • Child over 2 years and under 30 kg: 5 mg (5 ml) once daily
    • Child over 30 kg and adult: 10 mg (1 tab) once daily

    Duration

    • As short as possible (a few days).

    Contra-indications, adverse effects, precautions

    • Administer with caution and reduce the dose (administer every other day) in patients with severe renal or hepatic impairment.
    • May cause: headache, dizziness, drowsiness (caution when driving/operating machinery), nervousness, insomnia, increased appetite, rash.
    • Monitor combination with: 
      • central nervous system depressants (opioid analgesics, antipsychotics, sedatives, antidepressants, etc.);
      • erythromycin, fluconazole, fluoxetine, amiodarone, ritonavir, cimetidine (increased plasma concentrations of loratadine).
    • Avoid alcohol during treatment (increased risk of adverse effects).
    • Pregnancy: avoid during the first trimester (uncertain risk of hypospadias)
    • Breast-feeding: no contra-indication

    Remarks

    • Loratadine is less sedating than promethazine.

    Storage

     
      Below 25 °C