NICLOSAMIDE oral

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    Therapeutic action

    • Anthelminthic (taenicide)

    Indications

    • Taeniasis: beef tapeworm (Taenia saginata), pork tapeworm (Taenia solium), dwarf tapeworm (Hymenolepis nana) and fish tapeworm (Diphyllobothrium latum)

    Forms and strengths

    • 500 mg chewable tablet

    Dosage and duration

    T. saginata, T. solium and D. latum

    • Child under 2 years: 500 mg single dose
    • Child from 2 to 6 years: 1 g single dose
    • Child over 6 years and adult: 2 g single dose
       

    H. nana

    • Child under 2 years: 500 mg on D1, then 250 mg once daily for 6 days
    • Child from 2 to 6 years: 1 g on D1, then 500 mg once daily for 6 days
    • Child over 6 years and adult: 2 g on D1, then 1 g once daily for 6 days

    Contra-indications, adverse effects, precautions

    • May cause: gastrointestinal disturbances.
    • Pregnancy: no contra-indication
    • Breast-feeding: no contra-indication

    Remarks

    • Chew or crush the tablets before swallowing with water.
    • In the event of vomiting, the single dose may be divided in 2 doses taken with an interval of one hour.
    • As niclosamide is a taenicide not a taenifuge, do not expect the patient to expel the worm, portions are voided in a partially digested form.
    • Niclosamide is not active against the larval form of T. solium (cysticercosis).

    Storage

     
    – Below 25 °C