NICOTINAMIDE = VITAMIN PP = VITAMIN B3 oral

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    Therapeutic action

    • Vitamin

    Indications

    • Treatment of pellagra

    Forms and strengths

    • 100 mg tablet

    Dosage and duration

    • Child and adult: 100 mg 3 times daily, with a diet rich in protein, until the patient is fully cured

    Contra-indications, adverse effects, precautions

    • Pregnancy and breast-feeding: avoid, except if clearly needed (safety is not established)

    Remarks

    • Nicotinamide is also called niacinamide.
    • Vitamin PP deficiency is common when diet is almost entirely based on sorghum, millet or maize.
    • Vitamin PP deficiency often occurs in association with other vitamin B-complex deficiency (thiamine, pyridoxine), especially in alcoholic patients.
    • Vitamin PP is usually one of the components of multivitamin preparations and B-complex (7.5 mg to 15 mg per tablet).
    • Nicotinic acid has a similar action to nicotinamide, but is no longer used because of its adverse effects, especially its vasodilator action.

    Storage

     
    – Below 25 °C