CLOXACILLIN oral

Prescription under medical supervision


Therapeutic action

– Penicillin antibacterial

Indications

– Impetigo (preferably use cefalexin for this indication)

Forms and strengths

– 250 mg and 500 mg capsules

Dosage and duration

– Child over 10 years: 15 mg/kg 3 times daily for 7 days (max. 3 g daily)
– Adult: 1 g 3 times daily for 7 days

Age

Weight

250 mg capsule

500 mg capsule

10 to < 13 years

30 to < 45 kg

2 cap x 3

1 cap x 3

13 to < 15 years

45 to < 55 kg

3 cap x 3

Adult

≥ 55 kg

4 cap x 3

2 cap x 3

Contra-indications, adverse effects, precautions

– Do not administer to patients with allergy to penicillin.
– Administer with caution to patients with allergy to cephalosporins (cross-sensitivity may occur) or severe renal impairment (reduce the dosage).
– May cause: gastrointestinal disturbances (particularly diarrhoea), allergic reactions sometimes severe; rarely, haematological disorders.
– Do not combine with methotrexate (increased methotrexate toxicity).
– Pregnancy: no contra-indication
– Breast-feeding: no contra-indication

Remarks

– Take between meals.
– Dicloxacillin, flucloxacillin and oxacillin are antibacterials used for the same indication.
– Also comes in powder for oral solution 125 mg/5 ml and 1 g capsules.
  Storage: below 25 °C -