IBUPROFEN oral

Prescription under medical supervision


Therapeutic action

– Analgesic, antipyretic, non-steroidal anti-inflammatory (NSAID)

Indications

– Mild to moderate pain, fever, rheumatic diseases

Forms and strengths

– 200 mg and 400 mg enteric-coated tablets
– 100 mg/5 ml oral suspension, with pipette graduated per kg of body weight (each kg graduation corresponds to 10 mg ibuprofen)

Dosage

– Pain, fever
Child over 3 months: 5 to 10 mg/kg 3 to 4 times daily (max. 30 mg/kg daily)
Child 12 years and over and adult: 200 to 400 mg 3 to 4 times daily (max. 1200 mg daily) 
In post-operative period, ibuprofen should be given on a regular basis, every 8 hours, rather than “as needed”.

Age

Weight

100 mg/5 ml susp.

200 mg tablet

400 mg tablet

3 months to < 6 years

5 to < 20 kg

1 pipette filled up to the graduation corresponding to the child's weight x 3

6 to < 10 years

20 to < 30 kg

1 pipette filled up to the graduation corresponding to the child's weight x 3

1 tab x 3

10 to < 12 years30 to < 40 kg1 tab x 4


≥ 12 years and adult


≥ 40 kg


2 tab x 3
or
1 tab x 4


1 tab x 3

– Rheumatic diseases
Child: up to 40 mg/kg daily maximum

Adult: up to 3200 mg daily maximum

Duration

– According to clinical response; post-operative pain: 8 days max.

Contra-indications, adverse effects, precautions

– Do not administer to children under 3 months, patients with allergy to NSAID, peptic ulcer, coagulation defects, haemorrhage, surgery with risk of major blood loss, severe renal or hepatic impairment, severe heart failure, severe malnutrition, uncorrected dehydration or hypovolaemia, severe infection.
– May cause: allergic reactions, epigastric pain, peptic ulcer, haemorrhage, renal impairment.
– Administer with caution to elderly or asthmatic patients.
– Do not combine with: methotrexate, anticoagulants and other NSAIDs.
– Monitor combination with diuretics and angiotensin-converting enzyme inhibitors (drink plenty of fluids to avoid renal failure).
– Pregnancy: avoid. CONTRA-INDICATED from the beginning of the 6th month. Use paracetamol.
– Breast-feeding: no contra-indication (short term treatment)

Remarks

– Take with meals. Doses must be taken at least 4 hours apart.
– Clean the graduated pipette after use. Shake the bottle before use.
– If ibuprofen alone does not provide pain relief, combine with paracetamol and/or an opioid analgesic.
  Storage: below 25 °C -  - 
Once opened, oral suspension must be stored between 8 °C and 15 °C.