LORATADINE oral

Prescription under medical supervision


Therapeutic action

 – H1 antihistamine

Indications

– Symptomatic treatment of minor allergic reactions (urticaria, allergic conjunctivitis, etc.)

Forms and strengths

– 5 mg/5 ml oral solution
– 10 mg tablet

Dosage

– Child over 2 years and under 30 kg: 5 mg (5 ml) once daily
– Child over 30 kg and adult: 10 mg (1 tab) once daily

Duration

– As short as possible (a few days).

Contra-indications, adverse effects, precautions

– Administer with caution and reduce the dose (administer every other day) in patients with severe renal or hepatic impairment.
– May cause: headache, dizziness, drowsiness, nervousness, insomnia, increased appetite, rash.
– Monitor combination with: 
• central nervous system depressants (opioid analgesics, antipsychotics, sedatives, antidepressants, etc.) and alcohol;
• erythromycin, fluconazole, fluoxetine, amiodarone, ritonavir, cimetidine (increased plasma concentrations of loratadine).
– Pregnancy: avoid during the first trimester (uncertain risk of hypospadias)
– Breast-feeding: no contra-indication

Remarks

– Less sedating than chlorphenamine and promethazine.
 Storage: below 25 °C -