– Antiemetic (dopamine antagonist)
– Symptomatic treatment of nausea and vomiting in adults
Forms and strengths
– 10 mg tablet
– Adult under 60 kg: 5 mg 3 times daily
– Adult over 60 kg: 10 mg 3 times daily
The interval between each dose should be at least 6 hours (even in the event of vomiting).
– A few days
Contra-indications, adverse effects, precautions
– Do not administer to children < 18 years and to patients with gastrointestinal haemorrhage, obstruction or perforation.
– Reduce the dose by half in patients with severe renal impairment.
– Administer with caution and monitor use in patients > 60 years and patients with epilepsy or Parkinson's disease.
– May cause: drowsiness (caution when driving/operating machinery), dizziness, confusion, extrapyramidal symptoms, seizures (especially in epileptics), allergic reactions; neuroleptic malignant syndrome (unexplained hyperthermia with neuromuscular disorders), exceptional but requiring immediate treatment discontinuation.
– Do not combine with levodopa (antagonism).
– Avoid combination with CNS depressants (opioid analgesics, antipsychotics, sedatives, antidepressants, antihistamines, etc.).
– Avoid alcohol during treatment.
– Pregnancy: no contra-indication
– Breast-feeding: no contra-indication
– Storage: below 25 °C - -