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Therapeutic action
- Antiprogestogen
Indications
- Termination of intra-uterine pregnancy up to 22 weeks after the last menstrual period, in combination with misoprostol
Forms and strengths
- 200 mg tablet
Dosage and duration
- 200 mg single dose, followed by the administration of misoprostol 1 to 2 days later
Contra-indications, adverse effects, precautions
- Do not administer to patients with chronic adrenal failure or severe uncontrolled asthma.
- May cause: gastrointestinal disturbances, vaginal bleeding, uterine contractions, headache.
- Breast-feeding: no contra-indication for a single dose; to be avoided if multiple doses
Remarks
- Do not use mifepristone in ectopic or molar pregnancy.