PARACETAMOL = ACETAMINOPHEN oral


Therapeutic action

– Analgesic, antipyretic

Indications

– Mild pain
– Fever

Forms and strengths

– 100 mg and 500 mg tablets
– 120 mg/5 ml oral suspension

Dosage

– Child under 1 month: 10 mg/kg 3 or 4 times daily, if necessary (max. 40 mg/kg daily) 
– Child 1 month and over: 15 mg/kg 3 or 4 times daily, if necessary (max. 60 mg/kg daily)
– Adult: 1 g 3 or 4 times daily, if necessary (max. 4 g daily)

Age

Weight

120 mg/5 ml susp.

100 mg tablet

500 mg tablet

< 1 month

< 4 kg

1.5 ml x 3

1 to < 3 months

4 to < 6 kg

2.5 ml x 3

½ tab x 3

3 months to < 1 year

6 to < 10 kg

4 ml x 3

1 tab x 3

1 to < 3 years

10 to < 15 kg

6 ml x 3

1½ tab x 3

3 to < 5 years

15 to < 20 kg

8 ml x 3

2 tab x 3

5 to < 9 years

20 to < 30 kg

12 ml x 3

3 tab x 3

9 to < 14 years

30 to < 50 kg

1 tab x 3

≥ 14 years and adult

≥ 50 kg

2 tab x 3

Duration

– According to clinical response

Contra-indications, adverse effects, precautions

– Administer with caution to patients with hepatic impairment.
– Do not exceed indicated doses, especially in children and elderly patients. Paracetamol intoxications are severe (hepatic cytolysis).
– Pregnancy: no contra-indication
– Breast-feeding: no contra-indication

Remarks

– For mild pain, paracetamol is used alone or in combination with an NSAID.
– For moderate pain, paracetamol is used in combination with an NSAID and codeine or tramadol.
– For severe pain, paracetamol is used in combination with an NSAID and morphine.
– Paracetamol is particularly recommended for patients allergic to aspirin, patients with a history of gastric problems and for pregnant and breast-feeding women and children.
– Paracetamol has no anti-inflammatory properties.
– Storage: below 25 °C -