RETINOL = VITAMIN A oral


Therapeutic action

– Vitamin

Indications

– Prevention of vitamin A deficiency
– Treatment of vitamin A deficiency (xerophthalmia)

Forms and strengths

– 200 000 IU capsule, i.e. about 8 drops (1 drop = 25 000 IU)

Dosage and duration

Prevention of vitamin A deficiency
Child under 6 months: 50 000 IU single dose
Child from 6 to 12 months: one dose of 100 000 IU every 4 to 6 months
Child over 1 year: one dose of 200 000 IU every 4 to 6 months

Treatment of vitamin A deficiency
Child under 6 months: 50 000 IU once daily on D1, D2 and D8 (or D15)
Child from 6 to 12 months: 100 000 IU once daily on D1, D2 and D8 (or D15)
Child over 1 year and adult: 200 000 IU once daily on D1, D2 and D8 (or D15)


Age

200 000 IU capsule

Prevention

Treatment

< 6 months

2 drops

2 drops

6 months to < 1 year

4 drops

4 drops

1 to < 5 years

1 cap

1 cap

≥ 5 years and adult

1 cap

Contra-indications, adverse effects, precautions

– Do not exceed indicated doses.
– Overdosage may cause: gastrointestinal disturbances, headache, raised intracranial pressure (bulging fontanelle in infants); foetal abnormalities.
Pregnancy:
Prevention: after delivery only, 200 000 IU single dose
Treatment: dosage depends on severity of eye lesions:
• Night blindness and Bitot's spots: 10 000 IU once daily or 25 000 IU once weekly for at least 4 weeks
• Corneal lesion: 200 000 IU once daily on D1, D2 and D8 (or D15)
Breast-feeding: no contra-indication at recommended doses

Remarks

– Do not swallow the capsule. Cut open the end of the capsule and squeeze the dose directly into the mouth.
– Administer routinely 2 doses (on D1 and D2) to children suffering from measles to prevent the complications of measles.
Storage: below 25 °C