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Therapeutic action
- Anthelminthic
Indications
- Fascioliasis (Fasciola hepatica and Fasciola gigantica infections)
- Paragonimiasis
Forms and strengths
- 250 mg tablet
Dosage and duration
Fascioliasis
- Child and adult: 10 mg/kg single dose
Paragonimiasis
- Child and adult: 10 mg/kg 2 times daily
Contra-indications, adverse effects, precautions
- Do not administer to patients with hypersensitivity to triclabendazole or other benzimidazoles (albendazole, flubendazole, mebendazole, tiabendazole).
- May cause: abdominal pain, mild fever, headache, dizziness.
- Pregnancy: no contra-indication
- Breast-feeding: no contra-indication
Remarks
- Take tablets after meals.
- Due to its efficacy, good tolerance, and ease of administration, triclabendazole is the drug of choice for fascioliasis.
- Bithionol may be used as an alternative to triclabendazole in the treatment of fascioliasis: 30 mg/kg daily for 5 days.
- Unlike infections with other flukes, fascioliasis does not respond to praziquantel.
Storage
– Below 25 °C