MICONAZOLE oral gel

Therapeutic action

• Antifungal

Indications

• Mild oropharyngeal candidiasis

Forms and strengths

• 2% oral gel (24 mg/ml) together with, depending on the manufacturer:
  • a 2.5 ml measuring spoon with 1.25 ml and 2.5 ml graduation
    or
  • a 5 ml measuring spoon with 2.5 ml and 5 ml graduation

Dosage

• Child from 6 months to 2 years: 1.25 ml 4 times daily 
• Child over 2 years and adult: 2.5 ml 4 times daily

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The oral gel should be kept in the mouth 2 to 3 minutes and then swallowed, or in young children, applied to the tongue and inside of each cheek.

Duration

• 7 days; 14 days of treatment may be necessary.

Contra-indications, adverse effects, precautions

• Do not administer:
  • to children under 6 months or patients with swallowing difficulties (risk of suffocation due to oral gel form);
  • in patients with hepatic impairment.
• Do not combine with antivitamin K agents (risk of haemorrhage), glibenclamide (increased hypoglycaemic effect), phenytoin (increased plasma concentration of phenytoin).
• May cause: nausea, taste disturbances.
• Pregnancy: no contra-indication
• Breast-feeding: no contra-indication

Remarks

• Use the measuring spoon provided and check the graduation.
• Administer between meals (preferably after meals).
• In patients with dentures, clean dentures with oral gel when removed.
• In the event of moderate or severe oropharyngeal candidiasis, use oral fluconazole.
• Miconazole oral gel is not included in the WHO list of essential medicines.

Storage