THIAMINE = VITAMIN B1 oral

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    Therapeutic action

    • Vitamin

    Indications

    • Vitamin B1 deficiencies: beriberi, alcoholic neuritis

    Forms and strengths

    • 50 mg tablet

    Also comes in 10 mg and 25 mg tablets.

    Dosage and duration

    Infantile beriberi

    • 10 mg once daily, until complete recovery (3 to 4 weeks)

     

    Acute beriberi

    • 50 mg 3 times daily for a few days, until symptoms improve, then 10 mg once daily until complete recovery (several weeks)

     

    Mild chronic deficiency

    • 10 to 25 mg once daily

    Contra-indications, adverse effects, precautions

    • No contra-indication, or adverse effects with oral thiamine.
    • Pregnancy: no contra-indication
    • Breast-feeding: no contra-indication

    Remarks

    • In the treatment of severe cases, the use of injectable thiamine is justified to correct the disorder as rapidly as possible, but is no longer justified when symptoms have improved.
    • Vitamin B1 deficiency often occurs in association with other vitamin B-complex deficiencies, especially in alcoholic patients.
    • Thiamine is also called aneurine.

    Storage

     
    –  In airtight non-metallic container 
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