AMOXICILLIN oral

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    Prescription under medical supervision

     

    Therapeutic action

    • Penicillin antibacterial

    Indications

    • Acute otitis media, streptococcal tonsillitis, sinusitis, bronchitis, pneumonia
    • Infection due to Helicobacter pylori (in combination with omeprazole and clarithromycin), leptospirosis, uncomplicated cutaneous anthrax
    • Typhoid fever if the strain is susceptible (recent drug susceptibility test)
    • Completion treatment following parenteral therapy with penicillins or cephalosporins

    Forms and strengths

    • 250 mg and 500 mg tablets or capsules
    • 250 mg dispersible scored tablet, for paediatric use
    • 125 mg/5 ml powder for oral suspension, to be reconstituted with filtered water

    Dosage

    Usual dosage (e.g. leptospirosis, tonsillitis, infection due to H. pylori)

    • Child: 25 mg/kg 2 times daily 
    • Adult: 1 g 2 times daily

     

    Age

    Weight

    125 mg/5 ml susp.

    250 mg tablet

    500 mg tablet

    < 3 months

    < 6 kg

    1 tsp x 2

    ½ tab x 2

    3 to < 24 months

    6 to < 12 kg

    2 tsp x 2

    1 tab x 2

    2 to < 8 years

    12 to < 25 kg

    4 tsp x 2

    2 tab x 2

    1 tab x 2

    ≥ 8 years and adult

    ≥ 25 kg

    4 tab x 2

    2 tab x 2

     

    Severe infections (e.g. typhoid fever) or suspicion of resistant pneumococci (e.g. pneumonia, otitis)

    • Child: 30 mg/kg 3 times daily (max. 3 g daily)
    • Adult: 1 g 3 times daily

     

    Age

    Weight

    125 mg/5 ml susp.

    250 mg tablet

    500 mg tablet

    < 3 months

    < 6 kg

    1 tsp x 3

    ½ tab x 3

    3 to < 24 months

    6 to < 12 kg

    2 tsp x 3

    1 tab x 3

    2 to < 8 years

    12 to < 25 kg

    4 tsp x 3

    2 tab x 3

    1 tab x 3

    ≥ 8 years and adult

    ≥ 25 kg

    4 tab x 3

    2 tab x 3

    Duration

    • Otitis media: 5 days
    • Tonsillitis: 6 days
    • Leptospirosis, typhoid fever: 7 days
    • Pneumonia, sinusitis, cutaneous anthrax: 7 to 10 days
    • H. pylori infection: 7 days

    Contra-indications, adverse effects, precautions

    • Do not administer to penicillin-allergic patients or patients with mononucleosis.
    • Administer with caution to patients allergic to cephalosporins (cross-sensitivity may occur).
    • May cause: gastrointestinal disturbances, allergic reactions, sometimes severe. In the event of allergic reaction, stop treatment immediately.
    • Reduce dosage in patients with severe renal impairment.
    • Do not combine with methotrexate.
    • Pregnancy and breast-feeding: no contra-indication

    Storage

     
    –  
     
    – Below 25 °C 
     
    For the oral suspension (powder or reconstituted suspension): follow manufacturer’s instructions.