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- Third-generation cephalosporin antibacterial
- Typhoid fever
- Acute cystitis in girls over 2 years, pregnant women and lactating women
- Acute pyelonephritis in adults
- Cervicitis and urethritis due to Neisseria gonorrhoeae (in combination with a treatment for chlamydia)
Forms and strengths
- 200 mg tablet
- 100 mg/5 ml powder for oral suspension, to be reconstituted with filtered water
- Child: 10 mg/kg 2 times daily (max. 400 mg daily)
- Adult: 200 mg 2 times daily
Acute cystitis in girls over 2 years
- 8 mg/kg once daily
Acute cystitis in pregnant and lactating women, acute pyelonephritis in adult
- 200 mg 2 times daily
Cervicitis and urethritis due to Neisseria gonorrhoeae
- Child: 8 mg/kg single dose
- Adult: 400 mg single dose
- Typhoid fever: 7 days
- Acute cystitis: 3 days for girls and 5 days for adults
- Acute pyelonephritis: 10 to 14 days
Contra-indications, adverse effects, precautions
- Do not administer to patients with allergy to cephalosporins.
- Administer with caution to penicillin-allergic patients (cross-sensitivity may occur) and in patients with severe renal impairment (reduce dosage).
- May cause: gastrointestinal disturbances (especially diarrhoea), headache, dizziness, allergic reactions (rash, pruritus, fever). In the event of allergic reaction, stop treatment immediately.
- Pregnancy: no contra-indication
- Breast-feeding: no contra-indication
- Cefixime is also used in the second-line treatment of shigellosis (child: 8 mg/kg once daily; adult: 400 mg once daily) for 5 days.
- Also comes in 400 mg capsules.
- Below 25 °C
For the oral suspension (powder or reconstituted suspension): follow manufacturer’s instructions.