MICONAZOLE oral gel

Prescription under medical supervision


Therapeutic action

– Antifungal

Indications

– Mild oropharyngeal candidiasis

Forms and strengths

– 2% oral gel (24 mg/ml) together with, depending on the manufacturer:
• a 2.5 ml measuring spoon with 1.25 ml and 2.5 ml graduation
or
• a 5 ml measuring spoon with 2.5 ml and 5 ml graduation

Dosage

– Child from 6 months to 2 years: 1.25 ml 4 times daily 
– Child over 2 years and adult: 2.5 ml 4 times daily

The oral gel should be kept in the mouth 2 to 3 minutes and then swallowed, or in young children, applied to the tongue and inside of each cheek.

Duration

– 7 days; 14 days of treatment may be necessary.

Contra-indications, adverse effects, precautions

– Do not administer:
• to children under 6 months or patients with swallowing difficulties (risk of suffocation due to oral gel form);
• in patients with hepatic impairment.
– Do not combine with antivitamin K agents (risk of haemorrhage), glibenclamide (increased hypoglycaemic effect), phenytoin (increased plasma concentration of phenytoin).
– May cause: nausea, taste disturbances.
– Pregnancy: no contra-indication
– Breast-feeding: no contra-indication

Remarks

– Use the measuring spoon provided and check the graduation.
– Administer between meals (preferably after meals).
– In patients with dentures, clean dentures with oral gel when removed.
– In the event of moderate or severe oropharyngeal candidiasis, use oral fluconazole.
– Miconazole oral gel is not included in the WHO list of essential medicines.
  Storage: below 25 °C -