Prescription under medical supervision

Therapeutic action

– Anticonvulsant


– Epilepsy, except absence seizure (petit mal)

Forms and strengths

– 100 mg tablet


– Child 1 month to < 12 years: initially 1.5 to 2.5 mg/kg 2 times daily. According to response, increase up to 2 to 4 mg/kg 2 times daily (max. 7.5 mg/kg 2 times daily or 300 mg daily).
– Child 12 years and over: initially 75 to 150 mg 2 times daily. According to response, increase up to 150 to 200 mg 2 times daily (max. 300 mg 2 times daily).
– Adult: initially 75 to 150 mg 2 times daily. According to response, increase up to 200 to 500 mg daily (max. 600 mg daily). 


– According to clinical response

Contra-indications, adverse effects, precautions

– Do not administer in case of hypersensitivity to phenytoin.
– May cause:
• gastro-intestinal disturbances: gingival hypertrophy, nausea, vomiting;
• blood disorders: monitor blood counts if possible and administer folic acid in case of prolonged use;
• neurological disorders: dizziness, visual disturbances, mental confusion;
• allergic reactions: cutaneous eruption, fever, adenopathy.
– Do not stop treatment abruptly, decrease daily doses gradually.
– It is not recommended to combine phenytoin with oral contraceptives, sulphonamides or chloramphenicol. Combination with many other drugs must be closely monitored (diazepam, phenobarbital, digoxin, corticosteroids, etc.).
– Pregnancy: avoid
– Breast-feeding: avoid


  Storage: below 25 °C - 
Never use phenytoin after expiry date (risk of underdosage).