FUROSEMIDE injectable

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    Prescription under medical supervision

     

    Therapeutic action

    • Diuretic

    Indications

    • Emergency treatment of:
      • Oedema caused by renal, hepatic or congestive heart failure
      • Hypertensive crisis (except that of pregnancy)
      • Pulmonary oedema

    Forms and strengths, route of administration

    • 20 mg in 2 ml ampoule (10 mg/ml) for IM or slow IV injection

    Dosage

    • Child: 0.5 to 1 mg/kg/injection
    • Adult: 20 to 40 mg/injection

     

    Repeat after 2 hours if necessary.

     

    For pulmonary oedema: if an initial IV injection of 40 mg does not produce a satisfactory response within one hour, the dose may be increased to 80 mg by slow IV injection.

    Duration

    • According to clinical response;
    • If prolonged use is required, change to oral treatment 3 hours after the last injection.

    Contra-indications, adverse effects, precautions

    • Do not administer in other types of oedema, especially those due to kwashiorkor.
    • Do not administer in case of hepatic encephalopathy.
    • May cause: hypokalaemia, especially in cases of cirrhosis, denutrition, congestive heart failure.
    • Closely monitor combination with digoxin (furosemide enhances toxicity of digoxin).
    • Pregnancy: CONTRA-INDICATED to treat hypertension in pregnancy
    • Breast-feeding: avoid (excreted in milk and may reduce milk production)

    Remarks

    • If doses greater than 50 mg are required, it is recommended that they be given by IV infusion.

    Storage

     
    –  Below 25 °C