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    Prescription under medical supervision


    Therapeutic action

    • Sedating H1 antihistamine


    • Symptomatic treatment of allergic reactions, when oral administration is not possible

    Forms and strengths, route of administration

    • 50 mg in 2 ml ampoule (25 mg/ml) for deep IM injection

    Dosage and duration

    • Adult: 25 to 50 mg single dose

    Contra-indications, adverse effects, precautions

    • Administer with caution and monitor use:
      • in elderly patients; 
      • in patients with prostate disorders, closed-angle glaucoma, epilepsy, orthostatic hypotension, severe renal or hepatic impairment;
      • in patients taking CNS depressants (opioid analgesics, antipsychotics, sedatives, antidepressants, etc.) or drugs known to have an anticholinergic effect (atropine, amitriptyline, chlorpromazine, etc.).
    • May cause:
      • drowsiness, dizziness, headache, confusion, hypotension, photosensitivity (protect skin from sun exposure); 
      • anticholinergic effects (dry mouth, constipation, blurred vision, tachycardia, disorders of micturition); 
      • rarely: seizures, extrapyramidal syndrome, neuroleptic malignant syndrome (unexplained hyperthermia with neuromuscular disorders), allergic reactions.
    • Avoid alcohol during treatment.
    • Pregnancy and breast-feeding: avoid


    – Below 25 °C